This Week in Startups

This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

133 episodes summarized Open in App

Episodes (500)

What VCs Really Think About Personal AI Agents | E2347

Oct 8, 2026

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Jason Mentors The Next Generation + Why AI Is Bad at Teaching (Aristotle Interview) | E2346

Oct 5, 2026

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Inside The Startup Building Uncensored AI (Abliteration AI) | EP 2345

Oct 3, 2026

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Justin Kan & Brian Chesky: The Rejections That Built Twitch and Airbnb | E2344

Sep 30, 2026

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Jason’s Put a $5K Bounty on His Dream Chrome Extension | E2338

Sep 28, 2026

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The 5 Companies Apple Must Buy

Sep 28, 2026

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A rogue OpenAI agent hacked Australia’s government. Does this matter? | E2342

Sep 25, 2026

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VCs Would Bet on Open-Source AI Over OpenAI and Anthropic | E2341

Sep 23, 2026

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Elon's New Hyperloop, Trump's AI Rename, and a Model That Won't Talk | E2340

Sep 21, 2026

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Hugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339

Sep 18, 2026

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Hugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339

Sep 18, 2026

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90% of AI prototypes never reach production (w/ Temporal's Samar Abbas) | AI Basics

Sep 15, 2026

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Ask Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337

Sep 14, 2026

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The Pentagon Wants Equity in AI Startups | E2336

Sep 11, 2026

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Becki DeGraw on founder vesting, advisor equity & the 4-term-sheet play

Sep 10, 2026

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Did OpenAI Steal the Navier-Stokes Solution? | E2335

Sep 9, 2026

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Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334

Sep 4, 2026

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Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Legal Basics

Sep 3, 2026

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VC experts on why Physical AI funding is heating up | E2333

Sep 2, 2026

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Are AI Agents forming "civilizations" or is this just a psy op? | 2332

Aug 31, 2026

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Breaking down Nvidia's Hugging Face and Poolside bets | E2331

Aug 28, 2026

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Bill Gates foresees massive AI job loss: these VCs disagree | E2330

Aug 26, 2026

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You Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal Basics

Aug 25, 2026

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China wants you to cheer for the robots taking your job | E2329

Aug 25, 2026

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Open source is going to win it all: Harvey proves it | E2328

Aug 21, 2026

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Taste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI Basics

Aug 20, 2026

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Neurosymbolic AI outperforms chatbots and product search | E2327

Aug 19, 2026

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Bittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326

Aug 17, 2026

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What we'll learn from Anthropic's $2-$3T IPO | E2325

Aug 15, 2026

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These robots could cut delivery costs by 80% | Next Unicorns

Aug 12, 2026

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Zuck's AI manifesto is a data center PR masterclass | E2323

Aug 11, 2026

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How AI splits startups into winners and losers | E2322

Aug 7, 2026

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Airtable's 80% off value crash: VCs explain why it's still a win | E2321

Aug 5, 2026

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How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320

Aug 3, 2026

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Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319

Jul 31, 2026

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Banning Chinese robots isn't regulatory capture | E2318

Jul 29, 2026

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While other cultivated meat companies are collapsing, this one turned a profit | E2317

Jul 27, 2026

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Why quantum has been "10 years away" for 30 years | E2316

Jul 24, 2026

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Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315

Jul 22, 2026

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The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314

Jul 20, 2026

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The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313

Jul 17, 2026

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A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312

Jul 15, 2026

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Jason turned $11 and one tweet into 1.1M views | E2311

Jul 13, 2026

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Danny Bernstein left Big Tech to fund farm-bots | E2310

Jul 10, 2026

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Why Data Is the Next $1 Trillion Market

Jul 8, 2026

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$100T is managed by "human duct tape" | E2308

Jul 6, 2026

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Why the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307

Jul 1, 2026

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Chamath on why young people need more agency, risk, and adventure

Jun 29, 2026

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Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305

Jun 27, 2026

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Why the Future of Video Games is Moving Back to the Dinner Table

Jun 24, 2026

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