Latent Space: The AI Engineer Podcast
The podcast by and for AI Engineers! In 2024, over 2 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0.We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny...
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Episodes (288)
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI
Jul 28, 2026
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Inside the Model Factory — Eiso Kant, Poolside AI
Jul 23, 2026
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🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
Jul 21, 2026
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🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
Jul 16, 2026
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Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
Jul 8, 2026
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🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
Jul 1, 2026
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Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks
Jun 24, 2026
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Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan
Jun 22, 2026
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The Professor of Outputmaxxing — Anjney Midha, AMP
Jun 18, 2026
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🔬 The Self-Driving Lab — Joseph Krause, Radical AI
Jun 17, 2026
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Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs
Jun 4, 2026
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🔬Scaling Past Informal AI - Carina Hong, Axiom Math
Jun 3, 2026
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⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build
Jun 3, 2026
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GitHub's plan for Agents — Kyle Daigle, GitHub
Jun 2, 2026
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Why Video Agent models are next — Ethan He, xAI Grok Imagine
Jun 1, 2026
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The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray
May 28, 2026
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🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026
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Giving Agents Computers — Ivan Burazin, Daytona
May 21, 2026
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Railway: The Agent-Native Cloud — Jake Cooper
May 20, 2026
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The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
May 18, 2026
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AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge
May 14, 2026
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🔬Doing Vibe Physics — Alex Lupsasca, OpenAI
May 5, 2026
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Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition
Apr 27, 2026
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AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)
Apr 23, 2026
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Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO
Apr 22, 2026
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🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik
Apr 20, 2026
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Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion
Apr 15, 2026
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Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony
Apr 7, 2026
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Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"
Apr 3, 2026
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Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun
Apr 2, 2026
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Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample
Mar 30, 2026
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🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik
Mar 24, 2026
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Dreamer: the Personal Agent OS — David Singleton
Mar 20, 2026
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Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop
Mar 17, 2026
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Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer
Mar 12, 2026
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NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)
Mar 10, 2026
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Cursor's Third Era: Cloud Agents
Mar 6, 2026
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Every Agent Needs a Box — Aaron Levie, Box
Mar 5, 2026
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METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity
Feb 27, 2026
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[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka
Feb 26, 2026
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🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI
Feb 25, 2026
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Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis
Feb 24, 2026
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⚡️The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data
Feb 23, 2026
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Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z
Feb 19, 2026
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Owning the AI Pareto Frontier — Jeff Dean
Feb 12, 2026
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🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery
Feb 12, 2026
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The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI
Feb 6, 2026
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🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White
Jan 28, 2026
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🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White
Jan 28, 2026
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⚡️ Prism: OpenAI's LaTeX "Cursor for Scientists" — Kevin Weil & Victor Powell, OpenAI for Science
Jan 27, 2026
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