20VC: Leading Anthropic's First Ever Round | Will Open Source Threaten Anthropic's Business | Do Margins Matter in a World of AI | Why Triple, Triple, Double, Double is Not Good Enough Today | Why Series A is Hard Today with Matt Murphy @ Menlo
July 27, 2026
AI Summary
5 min readMatt Murphy, a partner at Menlo Ventures, led his firm into Anthropic at a $4 billion valuation when the company was pre-revenue and pre-launch. The deal was controversial inside the firm because it did not fit the standard playbook: a $600 million venture fund typically writes $15 million checks for meaningful ownership, and Anthropic wanted a round that was too large for the venture vehicle and too early for the growth fund. Murphy's partnership chose flexibility over rigidity. "Let's just do this," he recalls the consensus being. "This is one of the biggest waves. We've pivoted the firm to be all in on AI. Let's jump on this thing." That first check was just over $10 million — a "starter check" that got Menlo in the door. Within months, Anthropic launched its model, revenue began building, and Amazon and Google came in as both capital partners and distribution partners. Menlo then led a $500 million-plus SPV, its first ever, and Murphy describes the capital-raising process as the most nerve-wracking period of his recent career — "having to be the person capital raising, talking to investors, getting an occasional turn down, having to answer second and third order questions." The experience gave him new empathy for founders.
Ownership, dilution, and the new math of venture
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What you'll learn
- 1 (04:08) **How Menlo Landed Anthropic** - Matt recounts the origin story of Menlo Ventures’ investment in Anthropic, from introduction to deal structure
- 2 (07:20) **On Ownership in an Outlier World** - Matt argues that owning a tiny piece of a massive winner is better than owning a large piece of a modest exit
- 3 (09:14) **Is Ownership Less Relevant Today?** - A debate on whether lower ownership percentages are now acceptable given larger outcome sizes
- 4 (10:09) **When Does Price Actually Matter?** - Matt explains Menlo’s approach to valuation and check sizing across stages
- 5 (11:37) **The $500M SPV: How Menlo Doubled Down on Anthropic** - The story of Menlo’s massive follow-on investment and the mechanics of the SPV
- 6 (14:50) **When to Take Money Off the Table** - Matt’s philosophy on selling vs. holding in a hyper-growth environment
- 7 (15:49) **The Most Nervous Moments as an Anthropic Shareholder** - Matt names the scariest episodes in the last 24 months
+ Full timestamped outline available in the app
Guests on this episode
Show Notes
Matt Murphy is a Partner at Menlo Ventures, who just raised $3 billion in fresh capital, its largest pool ever. Matt's portfolio includes Anthropic, Lovable, Legora, OpenRouter, Chai Discovery, Axiom, OpenEvidence and more.
AGENDA:
00:00 Why Menlo Broke All Its Investing Rules to Back Anthropic
09:00 Why Ownership Matters Less in an Outlier-Driven Venture Market
13:00 Do We Have an SPV Problem in Venture Today?
20:00 Do Margins Still Matter in AI?
23:00 Why Open Source Won't Derail Anthropic's Growth
26:00 Does Every Model Provider Need to Build Its Own Chips?
29:00 Why Anthropic Is Not a Threat to Legora
32:00 Why Series A Is the Hardest Place to Invest Today
36:00 Why Signalling Is B.S. and Every Fund Is Going Full Stack
42:00 Why Building a Company in Europe Is Hard Mode
47:00 Why Triple-Triple-Double-Double Is No Longer Venture-Scale Growth
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