The Peter Attia Drive
Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
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Episodes (464)
#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D.
Aug 31, 2026
#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease
Aug 24, 2026
#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D.
Aug 17, 2026
#403 ‒ Peptides: separating scientific promise from marketing hype
Aug 10, 2026
#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.
Aug 3, 2026
#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare
Jul 27, 2026
#400 ‒ AMA #87: Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks
Jul 20, 2026
#399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.
Jul 13, 2026
Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)
Jul 6, 2026
#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss
Jun 29, 2026
#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.
Jun 22, 2026
#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy
Jun 15, 2026
#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.
Jun 8, 2026
#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements
Jun 1, 2026
#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they're working for you
May 25, 2026
#392 - Genetic testing: when it's valuable, how to choose the right test, and what to do with the results
May 18, 2026
#391 ‒ Colorectal cancer screening: importance of early screening, colonoscopy as a screening and preventive tool, and how to build a personalized strategy
May 11, 2026
#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration
May 4, 2026
#389 - Thinking scientifically: why it's hard, why it matters, and a practical toolkit
Apr 27, 2026
#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives
Apr 20, 2026
#387 - AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field
Apr 13, 2026
#386 - Aging clocks—what they measure, how they work, and their clinical and real-world relevance
Apr 6, 2026
#385 - AMA #82: Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more
Mar 23, 2026
#384 - Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention
Mar 16, 2026
Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.
Jan 26, 2026
The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D.
Jan 19, 2026
AMA #79: A guide to cardiorespiratory training at any fitness level to improve healthspan, lifespan, and long-term independence
Jan 12, 2026
Women's health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D.
Jan 5, 2026
Building & Changing Habits | James Clear (#183 rebroadcast)
Dec 29, 2025
Special episode: Understanding true happiness and the tools to cultivate a meaningful life—insights from past interviews with Arthur Brooks
Dec 22, 2025
AMA #78: Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more
Dec 15, 2025
Ketogenic diet, ketosis & hyperbaric oxygen: metabolic therapies for weight loss, cognition, Alzheimer's & more | Dom D'Agostino, Ph.D.
Dec 8, 2025
The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences, | Carole Hooven, Ph.D.
Dec 1, 2025
The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green (#288 rebroadcast)
Nov 24, 2025
Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care | Antonio Bianco, M.D., Ph.D.
Nov 17, 2025
AMA #77: Dietary fiber and health outcomes: real benefits, overhyped claims, and practical applications
Nov 10, 2025
Women's sexual health: desire, arousal, and orgasms, navigating perimenopause, and enhancing satisfaction | Sally Greenwald, M.D., M.P.H.
Nov 3, 2025
Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more (re-broadcast)
Oct 27, 2025
AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — proven, promising, fuzzy, noise, or nonsense?
Oct 27, 2025
Rethinking protein needs for performance, muscle preservation, and longevity, and the mental and physical benefits of creatine supplementation and sauna use | Rhonda Patrick, Ph.D.
Oct 20, 2025
The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.
Oct 13, 2025
Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data
Oct 6, 2025
Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt
Sep 29, 2025
#365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere
Sep 22, 2025
AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more
Sep 15, 2025
A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.
Sep 8, 2025
Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D. (#287 rebroadcast)
Sep 1, 2025
Understanding anxiety: defining, assessing, and treating health anxiety, OCD, and the spectrum of anxiety disorders | Josh Spitalnick, Ph.D., A.B.P.P.
Aug 25, 2025
AMA #74: Sugar and sugar substitutes: weight control, metabolic effects, and health trade-offs
Aug 18, 2025
How to change your habits: why they form and how to build or break them | Charles Duhigg, M.B.A
Aug 11, 2025
How metabolic and immune system dysfunction drive the aging process, the role of NAD, promising interventions, aging clocks, and more | Eric Verdin, M.D.
Aug 4, 2025
Peter's takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6
Jul 28, 2025
A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D.
Jul 21, 2025
AMA #73: Preserving brain health, optimizing exercise programming, improving body composition, and more
Jul 14, 2025
Navigating bone health: early life influences and advanced strategies for improvement and injury prevention (#214 rebroadcast)
Jul 7, 2025
Skincare strategies, the science of facial aging, and cosmetic-intervention guidance | Tanuj Nakra, M.D. & Suzan Obagi, M.D.
Jun 30, 2025
What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W.
Jun 23, 2025
AMA #72: Fasting: benefits for body composition and disease prevention, potential risks, and Peter's updated practical framework
Jun 16, 2025
Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D.
Jun 9, 2025
Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.
Jun 2, 2025
Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C.
May 26, 2025
AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity
May 19, 2025
Women's sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.
May 12, 2025
Peter's takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly Podcast Summary #5
May 5, 2025
Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H.
Apr 28, 2025
Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.
Apr 21, 2025
AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies
Apr 14, 2025
The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D.
Apr 7, 2025
Aging well: Peter shares strategies for improving longevity with residents at a senior living center
Mar 31, 2025
Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D.
Mar 24, 2025
AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need
Mar 17, 2025
Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English
Mar 10, 2025
Peter's takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4
Mar 3, 2025
Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D.
Feb 24, 2025
AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more
Feb 17, 2025
The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.
Feb 10, 2025
Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D.
Feb 3, 2025
Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller
Jan 27, 2025
AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk
Jan 20, 2025
Optimizing endurance performance: metrics, nutrition, lactate, and more insights from elite performers | Olav Aleksander Bu (Pt. 2)
Jan 13, 2025
Autism, ADHD, and Anxiety: Understanding the rise in autism and a multidisciplinary approach to diagnosis and treatment of each condition in children | Trenna Sutcliffe, M.D.
Jan 6, 2025
Building & Changing Habits | James Clear
Dec 30, 2024
Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more
Dec 16, 2024
AMA #66: Optimizing nutrition for health and longevity: myth of a "best" diet, complexities of nutrition science, and practical steps for building a sustainable diet
Dec 9, 2024
Choices, costs, and challenges in US healthcare: insurance intricacies, drug pricing, economic impacts, and potential reforms | Saum Sutaria, M.D.
Dec 2, 2024
Optimizing life for maximum fulfillment | Bill Perkins
Nov 25, 2024
AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging
Nov 18, 2024
Peter's key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3
Nov 11, 2024
Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.
Nov 4, 2024
CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.
Oct 28, 2024
Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.
Oct 21, 2024
Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D.
Oct 14, 2024
AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape
Oct 7, 2024
Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2
Sep 30, 2024
Cycling phenom and Tour de France champion Tadej Pogačar reveals his training strategies, on-bike nutrition, and future aspirations
Sep 23, 2024
Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.
Sep 16, 2024
AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations
Sep 9, 2024
Improve your decision-making, frameworks for learning, backcasting, and more | Annie Duke
Sep 2, 2024
Life after near-death: a new perspective on living, dying, and the afterlife | Sebastian Junger
Aug 26, 2024
Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.
Aug 19, 2024
AMA #62: Protein's impact on appetite and weight management, and uric acid's link to disease and how to manage levels
Aug 12, 2024
A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.
Aug 5, 2024
Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more
Jul 29, 2024
The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D.
Jul 22, 2024
AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D.
Jul 15, 2024
Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D.
Jul 8, 2024
AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more
Jul 1, 2024
Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.
Jun 24, 2024
AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
Jun 17, 2024
Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
Jun 10, 2024
NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
Jun 3, 2024
A breakthrough in Alzheimer's disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.
May 27, 2024
Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage liver disease | Julia Wattacheril, M.D., M.P.H.
May 20, 2024
AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
May 13, 2024
Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?
May 6, 2024
Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna's death
Apr 29, 2024
Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.
Apr 22, 2024
The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.
Apr 15, 2024
AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency
Apr 8, 2024
Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.
Apr 1, 2024
Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.
Mar 25, 2024
Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu
Mar 18, 2024
AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity
Mar 11, 2024
Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK | Jason McCarthy
Mar 4, 2024
The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2
Feb 26, 2024
The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2
Feb 26, 2024
Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.
Feb 19, 2024
AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more
Feb 12, 2024
The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green
Feb 5, 2024
Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D.
Jan 29, 2024
Journal club with Andrew Huberman: the impact of light exposure on mental health and an immunotherapy breakthrough for cancer treatment
Jan 22, 2024
AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more
Jan 15, 2024
Overcoming addictive behaviors, elevating wellbeing, thriving in an era of excess, and the scarcity loop | Michael Easter, M.A.
Jan 8, 2024
James Clear: Building & Changing Habits (#183 rebroadcast)
Jan 1, 2024
Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.
Dec 18, 2023
AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more
Dec 11, 2023
Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D.
Dec 4, 2023
Cultivating happiness, emotional self-management, and more | Arthur Brooks Ph.D.
Nov 27, 2023
The world's most important doctor to millions in the war-torn and remote villages of Sudan | Tom Catena, M.D.
Nov 20, 2023
AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
Nov 13, 2023
Breast cancer: how to catch, treat, and survive breast cancer | Harold Burstein, M.D., Ph.D.
Nov 6, 2023
Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D.
Oct 30, 2023
Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
Oct 23, 2023
AMA #52: Hormone replacement therapy in women: practical applications and the role of compounding pharmacies
Oct 16, 2023
Performance-enhancing drugs and hormones: risks, rewards, and broader implications for the public | Derek: More Plates, More Dates
Oct 9, 2023
Prostate health: common problems, cancer prevention, screening, treatment, and more | Ted Schaeffer, M.D., Ph.D.
Oct 2, 2023
Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.
Sep 25, 2023
AMA #51: Understanding and improving your metabolic health
Sep 18, 2023
Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers
Sep 11, 2023
Good vs. bad science: how to read and understand scientific studies
Sep 4, 2023
Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
Aug 28, 2023
The latest in cancer therapeutics, diagnostics, and early detection | Keith Flaherty, M.D.
Aug 21, 2023
AMA #50: Genetics: how they impact disease risk, what you can do about it, testing, and more
Aug 14, 2023
Time, productivity, and purpose: insights from Four Thousand Weeks | Oliver Burkeman
Aug 7, 2023
Hip, knee, ankle, and foot: common injuries, prevention, and treatment options
Jul 31, 2023
Concussions and head trauma: symptoms, treatment, and recovery | Micky Collins, Ph.D.
Jul 24, 2023
AMA #49: Heart rate recovery, strength training, rucking, kidney function, and brain health
Jul 17, 2023
Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D.
Jul 10, 2023
Training for The Centenarian Decathlon: zone 2, VO2 max, stability, and strength | Peter Attia, M.D.
Jul 10, 2023
Cancer screening with full-body MRI scans and a seminar on the field of radiology | Rajpaul Attariwala, M.D., Ph.D. (#61 rebroadcast)
Jul 3, 2023
Men's Sexual Health: why it matters, what can go wrong, and how to fix it | Mohit Khera, M.D., M.B.A., M.P.H.
Jun 26, 2023
Women's sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D.
Jun 19, 2023
AMA #48: Blood pressure—how to measure, manage, and treat high blood pressure
Jun 12, 2023
Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Tommy Wood, M.D., Ph.D.
Jun 5, 2023
The endocrine system: exploring thyroid, adrenal, and sex hormones | Peter Attia, M.D.
May 29, 2023
Latest therapeutics in CVD, APOE's role in Alzheimer's disease and CVD, familial hypercholesterolemia, and more | John Kastelein, M.D., Ph.D.
May 22, 2023
AMA #47: Cold therapy: pros, cons, and its impact on longevity
May 15, 2023
Hormone replacement therapy and the Women's Health Initiative: re-examining the results, the link to breast cancer, and weighing the risk vs reward of HRT | JoAnn Manson, M.D.
May 8, 2023
Latest insights on Alzheimer's disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.
May 1, 2023
The impact of stress on our physical and emotional health | Robert Sapolsky, Ph.D. (#51 rebroadcast)
Apr 24, 2023
AMA #46: Optimizing brain health: Alzheimer's disease risk factors, APOE, prevention strategies, and more
Apr 17, 2023
Training principles for longevity | Andy Galpin, Ph.D. (PART II)
Apr 10, 2023
How the brain works, Andrew's fascinating backstory, improving scientific literacy, and more | Andrew Huberman, Ph.D.
Apr 3, 2023
OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation, main themes, and more
Mar 28, 2023
Preventing cardiovascular disease: the latest in diagnostic imaging, blood pressure, metabolic health, and more | Ethan Weiss, M.D.
Mar 20, 2023
AMA #45: Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent
Mar 13, 2023
Overcoming trauma, finding inner peace, and living a meaningful and fulfilling life | Lewis Howes
Mar 6, 2023
The history of the cell, cell therapy, gene therapy, and more | Siddhartha Mukherjee
Feb 27, 2023
The fentanyl crisis and why everyone should be paying attention | Anthony Hipolito
Feb 20, 2023
AMA #44: Peter's historical changes in body composition with his evolving dietary, fasting, and training protocols
Feb 13, 2023
#241 ‒ Living intentionally, valuing time, prioritizing relationships, and more keys to a rich life | Ric Elias (Part 2)
Feb 6, 2023
The confusion around HDL and its link to cardiovascular disease | Dan Rader, M.D.
Jan 30, 2023
The science of strength, muscle, and training for longevity | Andy Galpin, Ph.D. (PART I)
Jan 23, 2023
AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
Jan 16, 2023
Optimizing life for maximum fulfillment | Bill Perkins
Jan 9, 2023
Neurodegenerative disease: pathology, screening, and prevention | Kellyann Niotis, M.D.
Jan 2, 2023
James Clear: Building & Changing Habits (#183 rebroadcast)
Dec 26, 2022
Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more | Layne Norton, Ph.D.
Dec 19, 2022
Chris Hemsworth on Limitless, longevity, and happiness
Dec 12, 2022
AMA #42: Optimizing sleep - bedtime routine, molecule regimen, sleep trackers, sauna, & more
Dec 5, 2022
Shoulder, elbow, wrist, and hand: diagnosis, treatment, and surgery of the upper extremities | Alton Barron, M.D.
Nov 28, 2022
A masterclass on insulin resistance—mechanisms and implications | Gerald Shulman, M.D., Ph.D. (#140 rebroadcast)
Nov 21, 2022
AMA #41: Medicine 3.0, developments in the field of aging, healthy habits in times of stress, and more
Nov 14, 2022
Cardiovascular disease in women: prevention, risk factors, lipids, and more | Erin Michos, M.D.
Nov 7, 2022
Understanding cardiovascular disease risk, cholesterol, and apoB
Oct 31, 2022
Improving body composition, female-specific training principles, and overcoming an eating disorder | Holly Baxter, APD
Oct 24, 2022
AMA #40: Body composition, protein, time-restricted feeding, fasting, DEXA scans, and more
Oct 17, 2022
The science of happiness | Arthur Brooks, Ph.D.
Oct 10, 2022
The comfort crisis, doing hard things, rucking, and more | Michael Easter, MA
Oct 3, 2022
Dietary protein: amount needed, ideal timing, quality, and more | Don Layman, Ph.D.
Sep 26, 2022
AMA #39: The Centenarian Decathlon, zone 2, VO2 max, and more
Sep 19, 2022
How nutrition impacts longevity | Matt Kaeberlein, Ph.D
Sep 12, 2022
Understanding sleep and how to improve it
Sep 5, 2022
Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.
Aug 29, 2022
Dialectical behavior therapy (DBT): skills for overcoming depression , emotional dysregulation, and more | Shireen Rizvi, Ph.D., ABPP
Aug 22, 2022
AMA #38: Can you exercise too much?
Aug 15, 2022
Exercise, VO2 max, and longevity | Mike Joyner, M.D.
Aug 8, 2022
Metabolomics, NAD+, and cancer metabolism | Josh Rabinowitz, M.D., Ph.D.
Aug 1, 2022
The gut-brain connection | Michael Gershon, M.D.
Jul 25, 2022
AMA #37: Bone health—everything you need to know
Jul 18, 2022
Liquid biopsies and cancer detection | Max Diehn, M.D. Ph.D.
Jul 11, 2022
Earning the gift of life | Ric Elias (#79 rebroadcast)
Jul 4, 2022
The neuroscience of obesity | Stephan Guyenet, Ph.D.
Jun 27, 2022
AMA #36: Fruits & vegetables—everything you need to know
Jun 20, 2022
Lp(a) and its impact on heart disease | Benoît Arsenault, Ph.D.
Jun 13, 2022
Medical mistakes, patient safety, and the RaDonda Vaught case | Marty Makary, M.D., M.P.H.
Jun 6, 2022
The Art of Stability | Beth Lewis (Ep. #131 Rebroadcast)
May 30, 2022
Tragedy, grief, healing, and finding happiness | Kelsey Chittick
May 23, 2022
AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin
May 16, 2022
Exercising for longevity: strength, stability, zone 2, zone 5, and more
May 9, 2022
Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)
May 2, 2022
Centenarians, metformin, and longevity | Nir Barzilai, M.D.
Apr 25, 2022
AMA #34: What Causes Heart Disease?
Apr 18, 2022
Peter on nutrition, disease prevention, sleep, and more — looking back on the last 100 episodes
Apr 11, 2022
In remembrance of Sarah Hallberg, D.O., M.S. (Ep. #162 Rebroadcast)
Apr 4, 2022
Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
Mar 28, 2022
AMA #33: Hydration—electrolytes, supplements, sports drinks, performance effects, and more
Mar 21, 2022
Running, overcoming challenges, and finding success | Ryan Hall
Mar 14, 2022
Eye health—everything you need to know | Steven Dell, M.D.
Mar 7, 2022
The science of obesity & how to improve nutritional epidemiology | David Allison, Ph.D.
Feb 28, 2022
AMA #32: Exercise, squats, deadlifts, BFR, and TRT
Feb 21, 2022
Freedom, PTSD, war, and life through an evolutionary lens | Sebastian Junger
Feb 14, 2022
How fructose drives metabolic disease | Rick Johnson, M.D.
Feb 7, 2022
AMA #31: Heart rate variability (HRV), alcohol, sleep, and more
Jan 31, 2022
COVID Part 2: Masks, long COVID, boosters, mandates, treatments, and more
Jan 24, 2022
Revolutionizing our understanding of mental illness with optogenetics | Karl Deisseroth M.D., Ph.D.
Jan 17, 2022
Paul Conti, M.D.: How to heal from trauma and break the cycle of shame
Jan 10, 2022
COVID-19: Current state of affairs, Omicron, and a search for the end game
Jan 3, 2022
Iñigo San Millán, Ph.D.: Zone 2 Training and Metabolic Health (Ep. #85 Rebroadcast)
Dec 27, 2021
AMA #30: How to Read and Understand Scientific Studies
Dec 20, 2021
Sam Apple: The Warburg Effect—Otto Warburg's cancer metabolism theory
Dec 13, 2021
Patrick Radden Keefe: The opioid crisis—origin, guilty parties, and the difficult path forward
Dec 6, 2021
Allan Sniderman, M.D.: Cardiovascular disease and why we should change the way we assess risk
Nov 29, 2021
Rick Johnson, M.D.: Metabolic Effects of Fructose (Ep. #87 Rebroadcast)
Nov 22, 2021
AMA #29: GLP-1 Agonists—The Future of Treating Obesity?
Nov 15, 2021
James Clear: Building & changing habits
Nov 8, 2021
David Nutt: Psychedelics & Recreational Drugs
Nov 1, 2021
Robert Gatenby, M.D.: Viewing cancer through an evolutionary lens and why this offers a radically different approach to treatment
Oct 25, 2021
AMA #28: All things testosterone and testosterone replacement therapy
Oct 18, 2021
Jeremy Loenneke, Ph.D.: The science of blood flow restriction—benefits, uses, and what it teaches us about the relationship between muscle size and strength
Oct 11, 2021
Lance Armstrong: The rise, fall, and growth of a cycling legend
Oct 4, 2021
Steven Rosenberg, M.D., Ph.D.: The development of cancer immunotherapy and its promise for treating advanced cancers
Sep 27, 2021
AMA #27: The importance of muscle mass, strength, and cardiorespiratory fitness for longevity
Sep 20, 2021
Matt Kaeberlein, Ph.D.: The biology of aging, rapamycin, and other interventions that target the aging process
Sep 13, 2021
Lawrence Wright: The 20th anniversary of the 9/11 attacks: reflections on how they happened, and lessons learned and not learned
Sep 6, 2021
AMA #26: Continuous glucose monitors, zone 2 training, and a framework for interventions
Aug 23, 2021
Esther Perel: The effects of trauma, the role of narratives in shaping our worldview, and why we need to accept uncomfortable emotions
Aug 16, 2021
Steve Austad, Ph.D.: The landscape of longevity science: making sense of caloric restriction, biomarkers of aging, and possible geroprotective molecules
Aug 9, 2021
AMA #25: Navigating the complexities and nuances of cancer screening
Jul 26, 2021
Katherine Eban: COVID-19 Lab Leak: Examining all sides of the debate and discussing barriers to a full investigation
Jul 19, 2021
Hugh Jackman: Reflections on acting, identity, personal transformation, and the significance of being Wolverine
Jul 12, 2021
Gary Taubes: Bad science and challenging the conventional wisdom of obesity
Jun 28, 2021
Patricia Corby, D.D.S.: Importance of oral health, best hygiene practices, and the relationship between poor oral health and systemic disease
Jun 21, 2021
AMA #24: Deep dive into blood glucose: why it matters, important metrics to track, and superior insights from a CGM
Jun 14, 2021
Amanda Smith, M.D.: Diagnosing, preventing, and treating Alzheimer's disease, and what we can all learn from patients with dementia
Jun 7, 2021
Layne Norton, Ph.D.: Building muscle, losing fat, and the importance of resistance training
May 24, 2021
Sarah Hallberg, D.O., M.S.: Challenging the status quo of treating metabolic disease, and a personal journey through a grim cancer diagnosis
May 17, 2021
AMA #23: All Things Nicotine: deep dive into its cognitive and physical benefits, risks, and mechanisms of action
May 10, 2021
Paul Offit, M.D.: The latest on COVID-19 vaccines and their safety, herd immunity, and viral variants
May 3, 2021
Peter Hotez, M.D., Ph.D.: Evolution of the anti-vaccine movement, the causes of autism, and COVID-19 vaccine state of affairs
Apr 26, 2021
Brian Deer: A tale of scientific fraud—exposing Andrew Wakefield and the origin of the belief that vaccines cause autism
Apr 19, 2021
AMA #22: Losing fat and gaining fat: the lessons of fat flux
Apr 12, 2021
Jake Muise: Humanely harvesting axis deer while alleviating its impact on Hawaii's vulnerable ecosystems
Apr 5, 2021
Chris Sonnenday, M.D.: The history, challenges, and gift of organ transplantation
Mar 29, 2021
Steve Levitt, Ph.D.: A rogue economist's view on climate change, mental health, the ethics of experiments, and more
Mar 22, 2021
AMA #21: Deep dive into olive oil, high-intensity exercise, book update, and more
Mar 15, 2021
Michael Rintala, D.C.: Principles of Dynamic Neuromuscular Stabilization (DNS)
Mar 8, 2021
Alex Hutchinson, Ph.D.: Translating the science of endurance and extreme human performance
Mar 1, 2021
Senator Bill Frist, M.D.: A modern Renaissance man's journey through science, politics, and business
Feb 22, 2021
AMA #20: Simplifying the complexities of insulin resistance: how it's measured, how it manifests in the muscle and liver, and what we can do about it
Feb 15, 2021
Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the Interventions Testing Program
Feb 8, 2021
Hussein Yassine, M.D.: Deep dive into the "Alzheimer's gene" (APOE), brain health, and omega-3s
Feb 1, 2021
Guy Winch, Ph.D.: Emotional first aid and how to treat psychological injuries
Jan 25, 2021
AMA #19: Deep dive on Zone 2 training, magnesium supplementation, and how to engage with your doctor
Jan 18, 2021
Phil Maffetone: Optimizing health and performance through maximal aerobic function
Jan 11, 2021
John Ioannidis, M.D., D.Sc.: Why most biomedical research is flawed, and how to improve it
Jan 4, 2021
Robert Abbott: The Bobby Knight story—a cautionary tale of unchecked anger, ego, and winning at all costs
Dec 21, 2020
AMA #18: Deep dive: sugar and sugar substitutes
Dec 14, 2020
Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
Dec 7, 2020
Kristin Neff, Ph.D.: The power of self-compassion
Nov 30, 2020
Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer's disease prevention—patient and doctor perspectives
Nov 23, 2020
Paul Offit, M.D.: An expert perspective on COVID-19 vaccines
Nov 16, 2020
AMA #17: Body composition methods tour de force, insulin resistance, and Topo Chico
Nov 9, 2020
BJ Miller, M.D.: How understanding death leads to a better life
Nov 2, 2020
James O'Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise.
Oct 26, 2020
Vinay Prasad, M.D., M.P.H: Hallmarks of successful cancer policy
Oct 19, 2020
AMA #16: Exploring hot and cold therapy
Oct 12, 2020
Beth Lewis: The Art of Stability: Learning about pain, mitigating injury, and moving better through life
Oct 5, 2020
Carol Tavris, Ph.D. & Elliot Aronson, Ph.D.: Recognizing and overcoming cognitive dissonance
Sep 28, 2020
Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology
Sep 21, 2020
Irene Davis, Ph.D.: The evolution of the foot, running injuries, and minimalist shoes
Sep 14, 2020
AMA #3 with sleep expert, Matthew Walker, Ph.D.: Fasting, gut health, blue light, caffeine, REM sleep, and more
Sep 7, 2020
Matthew Walker, Ph.D.: Sleep and immune function, chronotypes, hygiene tips, and addressing questions about his book
Aug 31, 2020
John Arnold: The most prolific philanthropist you may not have heard of
Aug 24, 2020
AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more
Aug 17, 2020
Joan Mannick, M.D. & Nir Barzilai, M.D.: Rapamycin and metformin—longevity, immune enhancement, and COVID-19
Aug 10, 2020
Lori Gottlieb: Understanding pain, therapeutic breakthroughs, and keys to enduring emotional health
Aug 3, 2020
Azra Raza, M.D.: Why we're losing the war on cancer
Jul 27, 2020
AMA with Dom D'Agostino, Ph.D., Part II of II: Ketosis for cancer and chronic disease, hyperbaric oxygen therapy, and the effect of ketosis on female health
Jul 20, 2020
Terry Real: Breaking the cycle of shame, anger, and depression
Jul 13, 2020
Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging
Jul 6, 2020
Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19
Jun 29, 2020
AMA with Dom D'Agostino, Ph.D., Part I of II: Ketogenic diet, exogenous ketones, and exercise
Jun 22, 2020
David Watkins, Ph.D.: A masterclass in immunology, monoclonal antibodies, and vaccine strategies for COVID-19
Jun 15, 2020
Eileen White, Ph.D.: Autophagy, fasting, and promising new cancer therapies
Jun 8, 2020
Normative errors—a conversation with my daughter about current events
Jun 3, 2020
Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it
Jun 1, 2020
AMA #14: What lab tests can (and cannot) inform us about our overall objective of longevity
May 18, 2020
Lew Cantley, Ph.D.: Cancer metabolism, cancer therapies, and the discovery of PI3K
May 11, 2020
John Dudley: The beauty in archery, the love of practice, and a model system for life
May 4, 2020
AMA #13: 3-day fasting, exogenous ketones, autophagy, and exercise for longevity
Apr 21, 2020
John Barry: 1918 Spanish flu pandemic—historical account, parallels to today, and lessons
Apr 17, 2020
Amesh Adalja, M.D.: Comparing COVID-19 to past pandemics, preparing for the future, and reasons for optimism
Apr 13, 2020
Paul Conti, M.D.: The psychological toll of a pandemic, and the societal problems it has highlighted
Apr 10, 2020
COVID-19 for kids with Olivia Attia
Apr 8, 2020
Looking back on the first 99 episodes: Strong Convictions, Loosely Held
Apr 6, 2020
Michael Osterholm, Ph.D.: COVID-19—Lessons learned, challenges ahead, and reasons for optimism and concern
Mar 31, 2020
Ryan Holiday: Finding stillness amidst chaos
Mar 27, 2020
Sam Harris, Ph.D.: COVID-19—Comprehending the crisis and managing our emotions
Mar 24, 2020
Peter Hotez, M.D., Ph.D.: Continuing the conversation on COVID-19
Mar 20, 2020
Qualy #129 - Evolutionary reasons to sleep
Mar 17, 2020
Peter Attia, M.D. and Paul Grewal, M.D.: Coronavirus (COVID-19) FAQ
Mar 15, 2020
Peter Hotez, M.D., Ph.D.: COVID-19: transmissibility, vaccines, risk reduction, and treatment
Mar 14, 2020
Qualy #125 - Hierarchies in healthcare, physician burnout, and a broken system
Mar 10, 2020
David Epstein: How a range of experience leads to better performance in a highly specialized world
Mar 9, 2020
Qualy #121 - The "art" of longevity: the challenge of preventative medicine and understanding risk
Mar 3, 2020
Luke Bennett, M.D.: The emotional, cognitive, and physical demands that make Formula 1 a unique and special sport
Mar 2, 2020
Qualy #120 - What is the difference between ketone salts and esters?
Feb 28, 2020
Mark Hyman, M.D.: The impact of the food system on our health and the environment
Feb 24, 2020
Qualy #116 - Dealing with anger in spots where you know it's coming
Feb 21, 2020
AMA with Jason Fried: Work-life balance, avoiding burnout, defining success, company culture, and more
Feb 17, 2020
Qualy #109 - How does one select the right physician as a patient?
Feb 11, 2020
AMA #12: Strategies for longevity (which don't require a doctor)
Feb 10, 2020
Qualy #106 - Does LDL cause heart disease?
Feb 5, 2020
Eric Topol, M.D.: Can AI empower physicians and revolutionize patient care?
Feb 3, 2020
Qualy #102 - Is the food industry still saying that all calories contribute equally to adiposity and insulin resistance?
Jan 29, 2020
Ryan Holiday: Stillness, stoicism, and suffering less
Jan 27, 2020
Qualy #99 - The steroid controversy: Mark's use of them and Peter's perspective
Jan 23, 2020
AMA #11: All things fasting
Jan 20, 2020
Qualy #94 - Comparing the two broad types of meditation, and Peter's favorite meditation apps
Jan 15, 2020
Paul Grewal, M.D.: Treating metabolic disease and strategies for long-term health
Jan 13, 2020
Qualy #89 - Cortisol and healthy aging
Jan 7, 2020
Rick Johnson, M.D.: Fructose—The common link in high blood pressure, insulin resistance, T2D, & obesity?
Jan 6, 2020
Qualy #85 - The past, present, and future of medicine, hospitals, and healthcare
Dec 31, 2019
Damon Hill: Overcoming loss, achieving success, and finding one's identity
Dec 30, 2019
Qualy #82 - What is the most common first presentation of heart disease?
Dec 25, 2019
Iñigo San Millán, Ph.D.: Mitochondria, exercise, and metabolic health
Dec 23, 2019
Qualy #80 - The four pillars of charity: water that helped it overcome the stigma of nonprofits and become successful
Dec 20, 2019
AMA #10: Low testosterone, hypothyroidism, building muscle (and preserving it while fasting)
Dec 16, 2019
Qualy #73 - How can we change the food system when 10 companies control almost 90 percent of the calories we consume in the US?
Dec 10, 2019
Bill Harris, Ph.D.: Omega-3 fatty acids
Dec 9, 2019
Qualy #69 - Advice to parents and kids for creating a sustainable environment that's going to prevent them from running into metabolic problems
Dec 3, 2019
Mark Messier: Leadership, personal growth, and performing under pressure
Dec 2, 2019
Qualy #65 - The three laws of medicine — Law #1: A strong intuition is much more powerful than a weak test
Nov 26, 2019
Debra Kimless, M.D. & Steve Goldner, J.D.: Cannabis – the latest science on CBD & THC
Nov 25, 2019
Qualy #61 - Rapamycin in cancer treatment
Nov 19, 2019
Celebrity AMA #1: Fasting, rapamycin, performance vs. longevity, and more
Nov 18, 2019
Qualy #57 - A primer on NAD+/NADH, its effect on lifespan/healthspan, and a review of the supplements
Nov 12, 2019
Ric Elias: Earning the gift of life
Nov 11, 2019
Qualy #53 - Screening for prostate cancer
Nov 5, 2019
Sasha Cohen: The price of achievement, and redefining success
Nov 4, 2019
Qualy #52 - Insights about berberine
Nov 1, 2019
AMA #2 with sleep expert, Matthew Walker, Ph.D.: short sleep mutants, optimal sleep environment, sleep apnea, & rapid fire questions
Oct 28, 2019
Qualy #46 - Rapamycin's effects on cancer, cardiovascular disease, and neurodegeneration
Oct 23, 2019
Kyle Kingsbury: Finding meaning, depression, and psychedelics
Oct 21, 2019
Qualy #43 - What are Peter's thoughts on fasting and ketosis for females?
Oct 17, 2019
David Light: Zantac recall due to cancer concerns – what you need to know
Oct 14, 2019
Qualy #38 - Finding meaning in struggle and why we are less happy than ever (David Foster Wallace)
Oct 9, 2019
Jason Fried: Optimizing efficiency and work-life balance
Oct 7, 2019
Qualy #33 - How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is critical of the current state of psychiatry
Oct 1, 2019
AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more
Sep 30, 2019
Qualy #29 - Fasting as a powerful drug in the toolbox of medicine (sneak peek of Paul Grewal's upcoming episode)
Sep 24, 2019
Dan Harris: 10% happier – meditation, kindness, and compassion
Sep 23, 2019
Qualy #26 - What is Peter looking to achieve and monitor with his blood glucose monitor?
Sep 18, 2019
Katherine Eban: Widespread fraud in the generic drug industry
Sep 16, 2019
Qualy #24 - What are the "ABCs" of Alzheimer's prevention?
Sep 13, 2019
David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
Sep 9, 2019
Qualy #19 - A unifying theory of aging
Sep 5, 2019
Ronesh Sinha, M.D.: Insights into the manifestation of metabolic disease in a patient population predisposed to metabolic syndrome, and what it teaches us more broadly
Sep 2, 2019
Qualy #16 - How much does cognitive activity ward off cognitive decline?
Aug 30, 2019
Marty Makary, M.D.: The US healthcare system—why it's broken, steps to fix it, and how to protect yourself
Aug 26, 2019
Qualy #9 - The importance of exercise for brain health
Aug 20, 2019
AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more
Aug 19, 2019
Qualy #6 - What are the best lab tests to request specifically for longevity
Aug 14, 2019
Vamsi Mootha, M.D.: Aging, type 2 diabetes, cancer, Alzheimer's disease, and Parkinson's disease – do all roads lead to mitochondria?
Aug 12, 2019
Qualy #1 - What are Peter's thoughts on alcohol consumption and health?
Aug 6, 2019
Rick Doblin, Ph.D.: MDMA— the creation, scheduling, toxicity, therapeutic use, and changing public opinion of what is possibly the single most important synthetic molecule ever created by our species
Aug 5, 2019
Zol Kryger, M.D.: Navigating the sometimes shady world of plastic surgery—understanding potential complications of common procedures and how to reduce your risk by choosing the right doctor and asking the right questions
Jul 29, 2019
AMA #7: Exercise framework, deadlifting, lower back pain, blood pressure, nootropics, CGM, and more
Jul 22, 2019
Keith Flaherty, M.D.: Deep dive into cancer—History of oncology, novel approaches to treatment, and the exciting and hopeful future
Jul 15, 2019
Rajpaul Attariwala, M.D., Ph.D.: Cancer screening with full-body MRI scans and a seminar on the field of radiology
Jul 8, 2019
The one-year anniversary episode with Olivia Attia: Reflecting on the past year and looking forward to exciting times ahead
Jul 2, 2019
Annie Duke, decision strategist: Poker as a model system for life—how to improve decision making, use frameworks for learning, and apply 'backcasting' to boost your odds for future success
Jul 1, 2019
Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness
Jun 24, 2019
AMA with sleep expert, Matthew Walker, Ph.D.: Strategies for sleeping more, sleeping better, and avoiding things that are disrupting sleep
Jun 17, 2019
Rick Rubin, legendary music producer: collaborating with sensitive psyche of greatest living musicians, and his personal story of weight loss and spiritual quest
Jun 10, 2019
Jocko Willink, retired Navy SEAL, Part II of II: Sleep, fasting, raising kids, discipline, taking ownership, and the impact of war
Jun 3, 2019
Jocko Willink, retired Navy SEAL, Part I of II: objective, strategy & tactics, leadership, protocols, dealing with death, and applying the many lessons learned from war
May 27, 2019
Kevin Sayer, CEO of Dexcom: Continuous glucose monitors – impact of food, sleep, and stress on glucose, the unmatched power of CGM to drive behavioral change, and the exciting future of CGM
May 20, 2019
AMA #6: Fasting framework, vitamin supplementation, antioxidants, time management, problem-solving, and more
May 13, 2019
Ethan Weiss, M.D.: A masterclass in cardiovascular disease and growth hormone - two topics that are surprising interrelated
May 6, 2019
The Ayrton Senna Episode (re-release): Celebrating the greatest driver in Formula 1 history and the cautionary tales of driven individuals
May 1, 2019
Robert Sapolsky, Ph.D.: The pervasive effect of stress - is it killing you?
Apr 29, 2019
AMA #5: calcium scores, centenarian olympics, exercise, muscle glycogen, keto, and more
Apr 22, 2019
Matthew Walker, Ph.D., on sleep – Part III of III: The penetrating effects of poor sleep from metabolism to performance to genetics, and the impact of caffeine, alcohol, THC, and CBD on sleep
Apr 15, 2019
Matthew Walker, Ph.D., on sleep – Part II of III: Heart disease, cancer, sexual function, and the causes of sleep disruption (and tips to correct it)
Apr 8, 2019
Matthew Walker, Ph.D., on sleep – Part I of III: Dangers of poor sleep, Alzheimer's risk, mental health, memory consolidation, and more.
Apr 1, 2019
Chris Masterjohn, Ph.D.: Navigating the many pathways to health and disease - NAD and sirtuins, methylation, MTHFR and COMT, choline deficiency and NAFLD, TMAO, creatine, and more
Mar 25, 2019
AMA #4: sleep, jet lag protocol, autophagy, metformin, and more
Mar 18, 2019
Jeremy Schaap, ESPN journalist: upsets, doping, triumphs, and the importance of sports
Mar 11, 2019
Alan Bauman, M.D.: The science of male and female hair restoration - how to protect, enhance, and restore the appearance and health of the hair and scalp
Mar 4, 2019
Avrum Bluming, M.D., and Carol Tavris, Ph.D.: Controversial topic affecting all women—the role of hormone replacement therapy through menopause and beyond—the compelling case for long-term HRT and dispelling the myth that it causes breast cancer
Feb 25, 2019
Jake Kushner, M.D.: How to thrive with type 1 diabetes and how everyone can benefit from the valuable insights
Feb 18, 2019
Tom Catena, M.D.: The world's most important doctor – to nearly a million patients – saving countless lives in the war-torn and remote villages of Sudan
Feb 11, 2019
Ted Schaeffer, M.D., Ph.D.: How to catch, treat, and survive prostate cancer
Feb 4, 2019
Francisco Gonzalez-Lima, Ph.D.: Advancing Alzheimer's disease treatment and prevention – is AD actually a vascular and metabolic disease?
Jan 28, 2019
Zubin Damania, M.D.: Revolutionizing healthcare one hilariously inspiring video at a time
Jan 21, 2019
Eric Chehab, M.D.: Extending healthspan and preserving quality of life
Jan 14, 2019
Nir Barzilai, M.D.: How to tame aging
Jan 7, 2019
Sam Harris, Ph.D.: The transformative power of mindfulness
Dec 20, 2018
Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin
Dec 17, 2018
Siddhartha Mukherjee, M.D., Ph.D.: new frontiers in cancer therapy, medicine, and the writing process
Dec 10, 2018
Navdeep Chandel, Ph.D.: metabolism, mitochondria, and metformin in health and disease
Dec 3, 2018
Thomas Seyfried, Ph.D.: Controversial discussion—cancer as a mitochondrial metabolic disease?
Nov 26, 2018
Apolo Anton Ohno: 8-time Olympic medalist – extreme training, discipline, pursuing perfection, and responding to adversity
Nov 19, 2018
Mark and Chris Bell: steroids, powerlifting, addiction, diet, training, helping others, documentaries, and living your best life
Nov 12, 2018
David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging
Nov 5, 2018
AMA #3: supplements, women's health, patient care, and more
Oct 29, 2018
Scott Harrison: transformation, finding meaning, and taking on the global water crisis
Oct 22, 2018
Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more
Oct 19, 2018
Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain
Oct 18, 2018
Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins
Oct 17, 2018
Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation
Oct 16, 2018
Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology
Oct 15, 2018
Dave Feldman: stress testing the lipid energy model
Oct 8, 2018
Richard Isaacson, M.D.: Alzheimer's prevention
Oct 1, 2018
Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations
Sep 24, 2018
Formula 1 (with Paul Conti): the best drivers, Ayrton Senna, and the cautionary tales of driven individuals
Sep 20, 2018
Paul Conti, M.D.: trauma, suicide, community, and self-compassion
Sep 17, 2018
Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system
Sep 10, 2018
Brett Kotlus, M.D.: How to look younger while you live longer
Sep 3, 2018
Corey McCarthy: Overcoming trauma, dealing with shame, finding meaning, changing the self-narrative, redemption, and the importance of gratitude
Aug 27, 2018
AMA #2: the Nothingburger — results from Peter's week-long fast between two weeks of nutritional ketosis — and answering questions on all things fasting
Aug 23, 2018
Matt Kaeberlein, Ph.D.: rapamycin and dogs — man's best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases
Aug 20, 2018
David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity?
Aug 13, 2018
Tom Bilyeu: nutrition, fasting, meditation, mindset, immortality, and the secret formula of fulfillment
Aug 6, 2018
Deep Dive: Lp(a) — what every doctor, and the 10-20% of the population at risk, needs to know
Jul 30, 2018
D.A. Wallach: music, medicine, cancer screening, and disruptive technologies
Jul 23, 2018
Dom D'Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer
Jul 16, 2018
AMA #1: alcohol, best lab tests, wearables, finding the right doc, racing, and more
Jul 9, 2018
Ron Krauss, M.D.: a deep dive into heart disease
Jul 2, 2018
Rhonda Patrick, Ph.D.: the performance and longevity paradox of IGF-1, ketogenic diets and genetics, the health benefits of sauna, NAD+, and more
Jul 2, 2018
Tim Ferriss: depression, psychedelics, and emotional resilience
Jul 2, 2018
Sneak Peek: The Peter Attia Drive
Jun 19, 2018