Golden State Killer, Crypto Convict, Genetic Genealogy - Megyn's "True Crime" Mega-Episode

May 3, 2026

AI Summary

5 min read

This Megyn Kelly Show "true crime" compilation features genetic genealogist CeCe Moore explaining investigative genetic genealogy (IGG), cold case investigator Paul Holes on the 2018 arrest of the Golden State Killer, and Ray Trapani recounting his role in the Centra Tech cryptocurrency fraud alongside friend Johnny B. Good.

Investigative Genetic Genealogy Mechanics

CeCe Moore, chief genetic genealogist at Parabon NanoLabs, traces IGG's roots from her hobbyist genealogy work around 2000, using Y-DNA and mitochondrial DNA for deep ancestry via cheek swabs and paper records. Autosomal DNA— inherited 50% from each parent, recombining rapidly—expanded possibilities after 23andMe's 2009 tests enabled relative matching via shared DNA segments.

For crimes, crime scene samples (semen, blood, touch DNA) go to private labs for SNP profiles (700,000+ markers), unlike law enforcement's STR profiles in CODIS. Profiles upload to opt-in databases like GEDmatch (500,000 law enforcement-eligible users) or FamilyTreeDNA. Distant cousins (3rd-6th) emerge; genealogists cluster matches by shared segments, build reverse family trees to common ancestors (e.g., great-great-grandparents), and narrow suspects via location, age, gender, and Parabon phenotyping (eye/hair color, ancestry predictions).

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What you'll learn

1 (00:00) **Episode Intro** - Megyn Kelly introduces true crime mega-episode on genetic genealogy, Golden State Killer, and crypto fraud
2 (01:00) **Genetic Genealogy Origins** - CeCe Moore explains her path from hobbyist to crime solver via Y-DNA, mtDNA, and family trees
3 (05:00) **Autosomal DNA Breakthrough** - Shift to autosomal DNA testing via 23andMe enables full family tree exploration
4 (16:00) **Crime-Fighting Databases** - GEDmatch and FamilyTreeDNA enable law enforcement uploads for distant relative matches
5 (29:00) **IGG Process Mechanics** - Crime scene DNA processed into SNP profile, clustered into genetic networks for tree-building
6 (38:00) **Phenotyping and Limitations** - Parabon predicts traits from DNA; ineffective for recent immigrants due to small databases
7 (40:00) **Idaho Murders Analysis** - Likely genetic genealogy ID'd Kohberger via knife sheath touch DNA and trash pull paternity match

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Show Notes

Megyn brings you the latest true crime mega-episode, featuring a deep dive on genetic genealogy with the expert on it, CeCe Moore, a look at the Golden State Killer, and an interview with the "crypto convict" Ray Trapani.

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https://www.devilmaycaremedia.com/megynkellyshow

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