The Checkup with Doctor Mike
The Checkup with Doctor Mike

How To Strengthen Your Brain As You Age | Dr. Majid Fotuhi

June 29, 2026

AI Summary

5 min read

In 2012, neurologist Dr. Majid Fotuhi left his comfortable faculty position at Johns Hopkins to open his own practice. The reason was simple: he kept seeing patients diagnosed with Alzheimer’s disease who had multiple treatable conditions—sleep apnea, depression, poor diet, chronic stress—that were being ignored. He believed that if you addressed all of those factors at once, you could see real cognitive improvement in months, not years. When he tested his 12-week multimodal program on patients with mild cognitive impairment, he found that half of them actually grew the volume of their hippocampus, the brain’s memory center, by 1 to 3 percent. That was unheard of.

The Brain Is Not Fixed—It Grows or Shrinks Based on Daily Habits

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What you'll learn

  • 1 (02:15) **The Mediterranean Diet & Brain Age** - Dr. Fotuhi explains why the Mediterranean diet is the most studied for brain health, citing data that it can make your brain appear up to 18 years younger.
  • 2 (04:31) **Origin Story: From a 7-Year-Old's Question to a Neurology Practice** - Dr. Fotuhi shares the childhood story that sparked his lifelong fascination with the brain's potential and how it led him to challenge conventional Alzheimer's diagnoses.
  • 3 (09:06) **The 12-Week Brain Fitness Program & Objective Proof** - Dr. Fotuhi describes building his own clinic and a multi-modal program that grew patients' hippocampi, providing objective MRI evidence of brain improvement.
  • 4 (16:07) **Neurogenesis: The Brain Can Grow New Neurons at Any Age** - Dr. Fotuhi presents the compelling evidence that the hippocampus can generate new neurons in humans, debunking the old dogma that the brain doesn't regenerate.
  • 5 (21:28) **Lifestyle Beats Drugs for Alzheimer's?** - Dr. Fotuhi compares the results of his multi-modal lifestyle program to the new amyloid-targeting drugs, revealing a massive difference in effectiveness.
  • 6 (29:14) **The Primary Care Trap: Why You Shouldn't Jump to Diagnose Alzheimer's** - Dr. Fotuhi advises primary care doctors to look for treatable causes of cognitive decline before labeling a patient with Alzheimer's disease.
  • 7 (33:48) **The Secret to Patient Buy-In: Brain Coaches & The "Aha!" Moment** - Dr. Fotuhi explains why his program was so successful at motivating patients, centering on personalized coaching and creating a powerful "aha!" moment.

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Show Notes

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Check out Dr. Majid Fotuhi's book here: https://a.co/d/0go6ywgt


00:00
01:30 His Background
08:35 Improving Memory
19:25 Alzheimers
26:38 Why are they buying in?
36:46 Adherence Long Term
43:15 Breathing Exercise
53:32 The Psychology Of Influence
58:30 How to reduce your own risk
1:11:52 Lifespan / Aging
1:19:30 Genetic Tests / Full Body MRI
1:32:30 Diet / Supplements
1:38:15 IQ Tests



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Executive Producer: Doctor Mike

Production Director and Editor: Dan Owens

Managing Editor and Producer: Sam Bowers

Editor and Designer: Caroline Weigum

Editor: Juan Carlos Zuniga


* Select photos/videos provided by Getty Images *


** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional **

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