The Art of Being Well
The Art of Being Well

Mast Cells & Autism, Viral Skin Issues + Organs Aging Faster | Ask Me Anything

September 3, 2026

AI Summary

5 min read

Mast Cells, Viral Skin Issues, and the Science of Cellular Aging

Dr. Will Cole opens this Ask Me Anything episode with a striking finding from a 2023 Stanford study: one in five people has an organ aging significantly faster than their other organs. For those individuals, the risk of dying increases by 15 to 50 percent. If the heart is the organ aging faster, there is a 250 percent increased risk of cardiac problems. A follow-up study published just weeks before this recording found that even within the same organ, different types of cells were aging at different rates. This research forms the backbone of Cole's forthcoming book Heal Your Cells, co-written with Dr. Josh Axe, which aims to translate cellular longevity science into practical protocols.

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What you'll learn

  • 1 (00:28) **Episode Introduction & Giveaway** - Dr. Will Cole and the team welcome listeners to an Ask Me Anything episode, explain how to submit questions, and outline the giveaway prizes.
  • 2 (04:32) **Introducing "Heal Your Cells"** - Dr. Cole gives a detailed preview of his upcoming book, co-authored with Dr. Josh Axe, focusing on cellular longevity and reversing chronic health problems.
  • 3 (21:24) **Question 1: Autism, Cold Urticaria & Mast Cell Activation** - A mother describes her four-year-old son with autism who develops severe hives from cold exposure (cold urticaria), requiring an EpiPen.
  • 4 (40:00) **Question 2: Viral Skin Warts on Hands** - A 23-year-old woman asks about stubborn, wart-like growths on her knuckles and fingers that have persisted for over a year.
  • 5 (54:02) **Episode Wrap-Up & Resources** - Dr. Cole closes the episode by directing listeners to his website for free articles, clinical resources, and information on telehealth services.
  • 6 Standout Quotes
  • 7 (12:14) "I love our publishers, but you know, they're going down the safe route. Like, are you really want to say reversing the irreversible? Yes. This is what we see all the time clinically. That's what we stand by. And this is what people are told. This is the point of the subtitle. It's obviously reversible if it's reversible."

+ Full timestamped outline available in the app

Guests on this episode

Dr. Will Cole

Show Notes

In this Ask Me Anything episode, Dr. Will Cole and his team introduce Heal Your Cells (co-written with Dr. Josh Axe) and the Stanford research behind it, then answer two listener questions: what's driving cold urticaria and hives in a 4-year-old with autism, and what wart-like growths on the knuckles of a 23-year-old are really communicating about immune health. They cover mast cell activation, histamine protocols, salicylic acid, bee propolis, Manuka honey, and the gut-immune connection — plus a story about a beta fish named Huffle that becomes a surprisingly relevant mold PSA. For all links mentioned in this episode, visit http://www.drwillcole.com/podcast


Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.

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