Best Peptides, Stem Cells, Testosterone & Exercise Hacks - Biohacking Roundtable - #1148
September 10, 2026
AI Summary
5 min readA 46-year-old physician on a panel of biohackers recently described going to Roatán, a small island off the coast of Honduras, for an experimental gene therapy designed to turn on a pre-existing gene. The procedure was not reversible, as she had initially been led to believe. This episode of Modern Wisdom features a roundtable with Dr. Gabrielle Lyon (a physician specializing in muscle-centric medicine), Ben Greenfield (a well-known biohacker and author), and Chris Williamson (the host). The conversation is a dense tour through the frontier of human optimization, covering peptides, stem cells, GLP-1 drugs, testosterone, and a host of other interventions. The throughline is a tension between powerful new tools for health and the systemic forces—from insurance models to FDA regulation to cultural stigma—that shape how those tools are used, often in ways that create new problems while solving old ones.
Peptides, Stem Cells, and the Regulatory Fight
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What you'll learn
- 1 (00:23) **Peptide Protocols & Personal Stacks** - The panel opens by sharing which peptides they personally use and for what specific purposes.
- 2 (03:50) **The GLP-1 Revolution & The Sarcopenia Trap** - The group discusses the massive rise of GLP-1 drugs and the looming public health crisis of muscle loss.
- 3 (06:56) **Biohacker "Bro Science": Biochargers & The Rockseva Lamp** - The panel shares experimental, data-light interventions they love, from EMF devices to psychedelic sound baths.
- 4 (14:03) **Hyperbaric, Hydrogen, & Selective Antioxidants** - The group explores the mechanisms behind hyperbaric oxygen therapy and various methods of hydrogen administration.
- 5 (20:44) **Sauna Heat, Cold Plunge Timing, & Heat Shock Proteins** - The panel debates the optimal sauna temperature for heat shock proteins and the real impact of cold plunging on muscle gains.
- 6 (24:41) **Resonance Breathing & The Ohm Lamp** - A deep dive into the science of resonance breathing and a new tool that makes it effortless.
- 7 (27:22) **Muse Stem Cells: The Super Soldier** - A groundbreaking explanation of a newly discovered stem cell phenotype and its implications for regenerative medicine.
+ Full timestamped outline available in the app
Guests on this episode
Show Notes
In this Biohacking Roundtable, we explore:
- What the best peptides for health & muscle building are.
- The latest biohacking tech that is real but sounds like science fiction.
- Which longevity supplements offer the most bang for your buck & are worth your time.
- The best diet and foods to eat to maximise longevity.
- and much more…
Guests:
- Dr Gabrielle Lyon is a functional medicine physician and Founder of the Institute of Muscle-Centric Medicine.
- Ben Greenfield is a biohacker, coach, author, speaker, and Ironman Triathlete.
- Brigham Buhler is a healthcare entrepreneur, founder and CEO of Ways2Well, and co-founder of ReviveRx Pharmacy.
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Timestamps:
(0:00) Science-Backed Peptide Regimes
(6:47) The Health Hacks Scientists Actually Swear By
(21:37) Do Heat Shock Proteins Really Matter?
(24:02) Why Resonance Breathing Is So Powerful
(27:17) Are MUSE Stem Cells the Next Big Breakthrough?
(36:23) Are GLP-1s Causing Too Much Muscle Loss?
(45:23) How GLP-1s Could Be Changing Desire
(54:12) Why Has Testosterone Become So Demonised?
(1:07:07) Should We Be Prioritising Testosterone?
(1:12:43) The Fight Against the Peptide Ban
(1:24:19) Health Freedom vs Protection: Where’s the Line?
(1:29:37) Is Plasmapheresis the Next Longevity Breakthrough?
(1:36:16) The Best Cost-Free Longevity Interventions
(1:44:44) Is Proteinmaxxing Overhyped?
(1:49:32) Is Fibre the Next Big Health Trend?
(1:58:24) Inside Ben’s Longevity Diet
(2:06:17) How Eating Speed Impacts GLP-1 Release
(2:07:31) Does Fasting Actually Work?
(2:10:28) Which Longevity Tools Are a Waste of Money?
(2:20:54) Should Microplastics Be Listed on Packaging?
(2:25:10) What’s the Next Big Biohacking Trend?
(2:33:52) What is EMF Exposure Actually Doing to Us?
(2:39:30) Do Air Scrubbers Actually Improve Your Health?<