FantasyPros - Fantasy Football Podcast
FantasyPros - Fantasy Football Podcast

Week 1 Lineup Winners: 6 Must-Start Fantasy Football Players (Ep. 2182)

September 11, 2026

AI Summary

5 min read

Derek Brown, the FantasyPros analyst known as "Downtown Derek Brown," opens the episode with a blunt read of the emotional state of fantasy managers after a rocky NFL kickoff: "If you started AJ Brown, you're not happy. You started Hunter Henry, you're not happy. You started anybody from the Seattle backfield, you're not happy." The episode is built around his weekly "Primer" — a 15,000- to 20,000-word living document published every Thursday during the regular season at FantasyPros.com. Brown describes it as "my love letter of every single week of the NFL season," designed to be navigable via search or game-to-game links so that a busy manager can "slide in, pony up to a barstool, get a drink real quick" and leave with actionable intel in about 30 minutes.

The Quarterback Play: Malik Willis as a Floor-Raising Streamer

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What you'll learn

  • 1 Week 1 Lineup Winners: 6 Must-Start Fantasy Football Players (Ep. 2182)
  • 2 (00:40) **Show Open & The Primer Explained** - Seth Wilcock and Derek Brown introduce the episode's mission: finding must-start players for Week 1
  • 3 (04:58) **Malik Willis (QB) - Rushing Floor Makes Him a Top-15 Play** - Derek argues Willis should be started over established QBs like Brock Purdy in Week 1
  • 4 (07:28) **Kenneth Gainwell (RB) - PPR Flex Against a Weak Bengals Linebacker Room** - Derek targets Gainwell as a value play in Week 1
  • 5 (09:44) **Marshawn Lloyd (RB) - ECR Has Him Way Too Low as RB29** - Derek is baffled that Lloyd is ranked as an RB3 despite being the clear starter
  • 6 (12:15) **Giveaway Announcement** - Chance to win a signed Kyren Williams Rams mini helmet
  • 7 (13:25) **DK Metcalf (WR) - Single-High Coverage Makes Him a Must-Start** - Derek explains the simple rule: start Metcalf against single-high, sit him against two-high

+ Full timestamped outline available in the app

Guests on this episode

Show Notes

Need some extra upside in your Week 1 lineup? Seth Woolcock and Derek Brown break down six must-start players who could outperform expectations, beginning with Malik Willis and his rushing upside against the Raiders before diving into Kenneth Gainwell and MarShawn Lloyd at running back.

The guys also explain why DK Metcalf could thrive against the Atlanta Falcons, why Chris Godwin has an enticing matchup with the Cincinnati Bengals, and why Mark Andrews could deliver a big Week 1 performance against the Indianapolis Colts. Get the matchup data, rankings context, and start/sit analysis you need before locking in your lineup.

Plus, Derek explains how to use the FantasyPros Primer to quickly research every matchup and player on your roster throughout the NFL season. Which Week 1 must-start are you trusting in your lineup?

Timestamps: (May be off due to ads)

Intro - 0:00:00

Malik Willis - 0:04:15

Kenneth Gainwell - 0:06:55

Marshawn Lloyd - 0:08:56

Kyren Williams Giveaway - 0:11:40

DK Metcalf - 0:12:56

Chris Godwin - 0:15:08

Mark Andrews - 0:17:10

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FantasyPros - Fantasy Football Podcast