All-In with Chamath, Jason, Sacks & Friedberg
All-In with Chamath, Jason, Sacks & Friedberg

Software Stocks Implode, Claude's Hit List, State of the Union Reactions, Trump's Tariff Pivot

February 28, 2026

AI Summary

5 min read

🎙️ The Speakers & Context

  • The Format: Host-led roundtable discussion among four core hosts.
  • The Key Players:
    • Chamath Palihapitiya: Investor (Social Capital), focuses on market mechanics, degrossing, and structural shifts like WACC/PE compression.
    • Jason Calacanis: Investor/podcaster, shares hands-on AI agent experiments at his firm, emphasizing operational efficiency.
    • David Sacks: Investor (Craft Ventures), PayPal mafia, dives into policy (tariffs, energy), contrarian on doomer narratives.
    • David Friedberg: Investor (Pattern, The Production Board), science expert, covers AI economics and biotech breakthroughs.
  • The Vibe: Technical, optimistic on AI productivity but combative on market uncertainty, politics, and NIMBY opposition.

🎣 The Executive Hook

  • The "One Big Idea": Markets have shifted from debating "when AI disrupts cash flows" to "if they survive at all, demanding massive valuation buffers (e.g., PE halved, WACC doubled) amid unpriceable event risk from AI agents/open-source models.
  • Why It Matters: Triggers degrossing by hedge funds, compresses SaaS multiples (from growth annuities to uncertain bets), and forces tech firms to slash stock-based comp for cash preservation during AI experimentation—amplifying the AI deflation curve in a top-ticking market.

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What you'll learn

  • 1 (01:30) **Anthropic's Market Disruptions**
  • 2 (07:38) **Viral AI Fan Fiction Substack**
  • 3 (11:52) **SaaS Uncertainty and Predictability Loss**
  • 4 (14:23) **AI Productivity and Consumptive Limits**
  • 5 (26:39) **Agent Builders and Economic Boom**
  • 6 (37:46) **Trump's Ratepayer Protection Pledge**
  • 7 (52:12) **State of the Union Highlights**

+ Full timestamped outline available in the app

Show Notes

(0:00) Bestie intros

(1:22) Claude's hit list, SaaS crash, and Citrini's AI letter

(30:39) Why Doomer narratives are more popular, valuable new AI jobs

(40:19) Understanding the Rate Payer Protection Pledge, what's behind datacenter opposition?

(52:13) State of the Union reactions

(1:03:58) Science Corner: Cure for blindness via Yamanaka Factors?

(1:10:17) SCOTUS strikes down tariffs, Trump pivots

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Intro Music Credit:

https://rb.gy/tppkzl

https://x.com/yung_spielburg

Intro Video Credit:

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Referenced in the show:

https://www.investing.com/news/stock-market-news/wolters-kluwer-relx-shares-slip-after-anthropic-unveils-aienhanced-legal-tool-4481124

https://www.barrons.com/articles/ibm-stock-had-worst-day-in-25-years-ai-disruption-fears-5f632d6c

https://www.forbes.com/sites/daniellechemtob/2026/02/24/forbes-daily-ibm-suffers-its-worst-day-since-the-dot-com-bubble

https://x.com/chamath/status/2027077786503164260

https://www.citriniresearch.com/p/2028gic

https://thedefiant.io/news/tradfi-and-fintech/credit-card-stocks-fall-after-citrini-ai-report

https://x.com/TurnerNovak/status/2026332990914101699

All-In with Chamath, Jason, Sacks & Friedberg